Located in beautiful SoCal we are a gobal service provider for manufacturing design services by delivering industrial automation solutions for semiconductor manufacturers. Recognized as Fortune 500 Company for 18th Straight Year, we are growing and ready to bring on some new talent.

Our ideal candidate will a solid background with SolidWorks PDM, Automation and Machine Design, very important for this role. Understand the Full Scope of Customers request and systems designs.

1.    Material handling

2.    Clean room

3.    Vision equipment

If you're seeking long-term growth opportunities with a strong leadership behind you, this role is for you.

Please email tmedley@mattsonresources.com

Located in beautiful SoCal we are a gobal service provider for manufacturing design services by delivering industrial automation solutions for semiconductor manufacturers. Recognized as Fortune 500 Company for 18th Straight Year, we are growing and ready to bring on some new talent.  

Our ideal candidate will have a strong background with at least 4/5 of these skill sets.  
1.    C# and .Net development with Visual Studio 
2.    Semiconductor industry standards including GEM 300 (SECS/GEM)
3.    PLC Programming and I/O controls knowledge 
4.    TwinCAT systems development and Beckhoff hardware 
5.    Motion control  (SCARA, 6-axis, cartesian) 
6.    Computer Vision systems 
7.    AI, deep learning applied to defect inspection and quality traceability 
Nice to have additional knowledge are: 
                GAMP 5 
                European CE standards 
                FDA standards

If you're seeking long-term growth opportuntiy with awesome leadership support, this position if for you. 

Please email - tmedley@mattsonresources.com

• Develop and manage company standards, specifications and procedures governing Distribution Integrity

• Management Program, specifically regarding Risk & Threats.

• Interpret state and federal codes, industry standards and Company specifications. Participate in, and provide technical input to, review of proposed changes in regulatory requirements affecting codes and standards. Recommend modifications to Company policy and procedures that reflect regulatory changes.

• Gather data, perform calculations and prepare designs to develop technically sound findings, conclusions and recommendations. Follow up on implementation of recommendations and/or acceptance of conclusions to assess accuracy and/or completeness.

• Manage and coordinate all activities leading to the successful completion of tasks and small projects including, seeping of project, selection of consultants and/or contractors, cost estimates, budgeting, permitting, design, material procurement and start-up.

• Stay abreast of the latest changes, trends and technological advancements in the industry through attendance at conferences and seminars, continuing education, literature, etc. Maintain familiarity with Company operations to effectively support client requests.

Qualifications:

• Must possess the ability to review problems and propose innovative solutions, which involve technical, operational, and economic issues, and may link new concepts and technologies.

• Requires knowledge of engineering practices and concepts and Company operating practices and policies. Experience in Distribution Operation is desirable.

• Understanding of systematic/scientific approaches to problem solving, and the ability to apply them in daily operations. Also able to effectively interact with various departments to maintain open lines of communication.

• Requires ability to identify the potential financial implications, as well as the impact that the project or task has on existing Company facilities, operating philosophies and procedures.

• Familiar with federal code, state code and other industry standards relating to natural gas business.

• Must be able to determine project requirements and the resources required for completion. Coordinates the activities of, and has overall responsibility for, multiple, concurrent projects and/or tasks, which require the ability to plan and manage work load so that assignments are completed on time and in proper priority.

• Must clearly and concisely communicate technical information and concepts with various levels of management in both formal and informal settings.

• Must be able to prepare written communications on technical and non-technical matters for various levels of management.

B.S. in Metallurgy, Mechanical, or Civil Engineering or other technical discipline required. Experience in statistical analysis and/or Risk Assessment it highly desirable. Completion of the state Engineer-In-Training or equivalent Company certificate is desirable. Licensed as a professional engineer in the state of California or equivalent professional certification is highly desirable.

Strong computer skills are required to demonstrate competency in company supported desktop software (i.e., Microsoft Products including Word, Excel, PowerPoint, and Visio). Knowledge of database environments (i.e., Access, SQL) is desirable

Expertise: Knowledge & Skills
•    Requires full working knowledge of relevant business practices and procedures in professional field. Uses standard theories, principles and concepts and integrates them to propose a course of action.
•    Provides direct or supervision to a group of employees, assigning tasks and checking work at frequent intervals. Accountabilities include work and people scheduling, performance management and recommendations for hiring decisions.
•    Judgement is required in resolving complex problems based on experience.
•    Contacts are primarily with department supervisors, leads, subordinates, and peers. Frequent contact with external contractors/vendors.

Required:
•    Bachelor's degree required or equivalent combination or education and experience.
•    06+ years related experience required.
Must have Supervisory experience of 3+ years
•    Applicable industry/professional certification preferred.
•    Ability to work non-standard schedule as needed.

Responsibilities: Essential Duties
•    Supervises employees, tasks and duties related to quality control within organization.
•    Develops, implements and assesses processes and policies designed to test products and services.
•    Monitors and evaluates current testing processes, making recommendations for improvements when necessary.
•    Enforces regulatory compliance.
•    Conducts visual and physical inspections of company products and materials.
•    Monitors the performance of the quality control staff, ensuring that the quality control department meets organizational objectives.
•    Responsible for personnel actions including (but not limited to) hiring, performance management and termination.
The job function listed is not exhaustive and shall also include any responsibilities as assigned by the Supervisor from time to time.

Expertise: Knowledge & Skills
•    Requires full working knowledge of relevant business practices and procedures in professional field. Uses standard theories, principles and concepts and integrates them to propose a course of action.
•    Provides direct or supervision to a group of employees, assigning tasks and checking work at frequent intervals. Accountabilities include work and people scheduling, performance management and recommendations for hiring decisions.
•    Judgement is required in resolving all day-to-day problems.
•    Contacts are primarily with department supervisors, leads, subordinates, and peers. Occasional contact with external contractors/vendors.

Required:
•    Bachelor's degree required or equivalent combination or education and experience.
•    04-06 years related experience required.
•    Applicable industry/professional certification preferred.
•    Ability to work non-standard schedule as needed.

Key Responsibilities:
Contribute to overall compound development via application of quantitative methods to integrate knowledge of PK, PD, patient characteristics, disease states, and drug—drug interactions to optimize dose selection, dosage regimens and study designs throughout drug development. Responsible for appropriate summarization and interpretation of results of PK/PD analyses with respect to their impact on development and clinical use of drugs. Independently or with assistance from senior members of the group whenever necessary, clinical pharmacologists will translate quantitative knowledge into strategic opportunities with key stake holders to drive development along the model-based drug development principles.
•    Accountable for all modeling and simulation activities in the program. Perform and/or liaise for modeling and simulation analysis of preclinical-clinical data, translational PK/PD data, up to first-in-human (FIH) and if applicable beyond FIH (dose/exposure-response analyses to guide dose regimen from pre-proof of concept (POC) studies and POC studies); Whenever appropriate perform and/or provide input and guidance to the prediction of clinical response and study outcomes of Phase 2b, and Phase 3 trials and to optimize trial designs. Consider alternate and appropriate dosing recommendations for special situations (e.g., drug interaction, food effect, pharmacogenomics effect, pediatric, elderly, renal impairment, hepatic impairment).
•    Partner with functional representatives in biology, chemistry, biomarker, translational medicine, CDTLs and clinicians to develop CPDP and design suitable early PKPD plans on projects
•    Engage discovery project teams early to aid in PKPD, biomarker, and efficacious dose prediction strategies
•    Design and execute PKPD modeling efforts to address the unique challenges pertinent to the project
•    Contribute to preparation of monographs, INDs and other documents as applicable to support clinical studies
•    Seamlessly transfer project knowledge/assets to the relevant team upon FIH (or an alternative mutually agreed upon point)
•    Where applicable, find common areas of need across projects (and possibly across TAs) that could benefit from a common modeling approach/platform
•    Mentor other CP colleagues in the science of preclinical PKPD modeling, simulation and efficacious dose prediction
•    Remain current with clinical and drug development information and methods in modeling and simulation by engaging with the scientific community (e.g., publishing, presenting at meetings, participating in special interest groups within professional societies, etc.) and internalize key learnings back to Janssen
•    Develop key product differentiation strategies based on a compound’s key attributes and relevant therapeutic landscape in CPDP; subsequently continue to liaise with key functional partners to provide product differentiation strategies throughout the drug development continuum.
•    Define regulatory strategy for CP and prepare CP contributions to regulatory documents including IBs, IND’s, briefing books, NDA / MAA submissions, bridging documents, post-approval filings, and responses to health authority questions and where appropriate represent CP in relevant external regulatory meetings (eg, End of Phase 2, pre-NDA / MAA, Advisory Committee meetings).
•    When requested, participate in the evaluation of potential business development opportunities.
•    Present and/or publish scientific data at conferences and in peer-reviewed journals, stay abreast of new emerging technologies in relevant scientific fields; identify new opportunities for applied scientific and technical advancement within the division.
•    Work effectively in matrix environment, managing CP deliverables in accordance with timelines and overall project goals.
•    Apply appropriate regulatory (eg: FDA, EMEA, ICH etc) guidelines in the design of clinical development plans and studies.
•    Apply relevant technical trainings/learnings to daily responsibilities, with focus of opportunistic deliver of value/impact. Where appropriate, serve as role model/mentor for junior staff

**Qualifications

Education:**
An M.S. Degree In Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, Or Relevant Biological Sciences Or PharmD With A Minimum Of Five (5) Years Of Pharmaceutical Development Experience With At Least Three (3) Years Of Relevant Experience Performing Progressively Advanced Duties At The Senior Scientist Level OR A PhD, MD Or Equivalent Degree In Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, Or Relevant Biological Sciences With A Minimum Of Four (4) Years Of Pharmaceutical Development Experience With At Least 3 Years Of Relevant Experience Performing Progressively Advanced Duties At The Senior Scientist Level.
Experience And Skills:

Required:
Demonstrated understanding of overall process of drug development and the overall pharmaceutical R&D process is required.
•    Has established a strong level of expertise and scientific reputation through multiple publications and presentations, preferred.
•    Broad drug development experience in one or multiple Therapeutic Areas and has the ability to lead and / or oversee multiple smaller clinical pharmacology programs, required.
•    Demonstrated understanding of model-based drug development, biopharmaceutics classification system (BCS), and biostatistics principles and tools (eg. gastroplus, simcyp, Winnonlin, NONMEM etc.) and demonstrated ability to apply these tools to enable rational and efficient drug development is required.
•    Demonstrated understanding of PK, PD, PK/PD, and Translational Medicine is required.
•    Good understanding of clinical drug development and the overall pharmaceutical R&D process is required.

Preferred:
•    Working knowledge of US, European, and Asian regulatory requirements and guidelines.
•    Working knowledge of clinical and regulatory landscape, disease processes and mechanisms, available treatment paradigms, and patient populations within assigned Therapeutic Area(s).
•    Previous working experience in the Neuroscience Therapeutic Area is desirable.

Responsibilities of the Senior Scientist will include:

•    Design and implement a highly efficient High Throughput Purification workflow at La Jolla, CA site
•    Lead the effort to identify, evaluate, implement and apply cutting-edge purification capabilities to support both chemical library samples and medchem singleton samples
•    Implement capabilities to support non-small molecule modalities, such as peptide, oligonucleotides and bio-conjugates
•    Lead an effective High Throughput Purification team to deliver fast turn-around purification services to meet business needs
•    Streamline the purification, compound registration and distribution workflow
•    Serve as a scientific expert in high throughput purification with both internal and external partners and provide recommendations regarding best practices and emerging new capabilities in Separation Sciences.
•    Ensure optimal interaction/communication and provide updates to Discovery Chemistry leadership
•    Maintain significant personal laboratory presence

Qualifications:
•    A minimum of a Master degree in Chemistry or related field with 7+ years of related experience is required; Ph.D. is a preferred
•    A minimum of 7 years’ experience in the biopharmaceutical industry with a proven track record of managing High Throughput Purification capability
•    In-depth knowledge and extensive experience in Analytical and Separation Sciences. Expert knowledge of modern analytical and purification techniques, such as mass-directed reverse phase preparative HPLC and SFC
•    Demonstrated experience with lab automation and compound distribution logistics
•    Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives are required
•    Up to 10% travel both domestically and internationally is required

The Principal Electrical Manufacturing Engineer’s responsibilities will include:
•    Apply knowledge of technical principles and process excellence (Lean / Six Sigma) to define, develop, maintain and optimize manufacturing and service processes for Electronics Business.
•    Use technical principles, problem solving skills, and data analysis to support and problem-solve for production and service at local, global, and third party suppliers through a robust supplier interface.
•    Drive incorporation of technical advancements, product improvements, and cost reductions through manufacturing enhancements, product changes, and part qualifications.
•    Work and lead initiatives to support manufacturing projects and goals (material qualification, supplier changes, part changes, product changes, product enhancements, equipment qualifications) through technical advancements, problem solving skills, and process excellence methodologies.
•    Lead key project initiatives (supplier transfers, part changes, system enhancements, line extensions, cost reductions, labor efficiency improvements, and quality and compliance excellence).
•    Provide ongoing support and training to the production/service personnel on new processes, process changes, and systems to increase quality and productivity in the build, test, and servicing of electronics products.
•    Understand and maintain assembly, test, and servicing processes, equipment, and tools to ensure availability of tools and equipment for the operators as required for local and global sites.
•    Manage change control for ongoing manufacturing changes, including change requests, process changes, Device Master Record, product specifications, test processes, and product service processes.
•    Deploy, review, and act upon meaningful metrics to measure, control, define, refine, and optimize processes and for process control and continuous improvement.
•    Perform other duties and responsibilities as assigned.

Requirements/Qualification:
•    Bachelor’s Degree in Electrical Engineering is required with a minimum of 7 years of relevant work experience; OR Master’s Degree in Engineering with a minimum of 5 years of work experience. Prior medical device industry experience is required.
•    Understanding of product and process change control, design control, MRP / Inventory processes, and Quality System requirements.
•    Familiarity with medical device regulations and governance documents (ISO13485, CFR820, etc).
•    Experience writing and executing protocols for validation of tools, fixtures, equipment, and process.
•    Must have the ability to train, coach and mentor operators on how to use the procedures effectively.
•    Capable of analyzing and solving complex problems through innovative thought and experience. Capable of making decisions based on data, analysis, and problem solving methods (ex: DMAIC) then acting quickly to deploy the resulting desired option.
•    Demonstrated experience with process excellence and continuous improvement in the manufacturing/service environment.
•    Experience working with suppliers of electronics components, subassemblies, and finished devices.
•    Experience writing, developing, and maintaining procedures for assembly, service, and test.
•    Strong communication and interpersonal skills. Ability to communicate clearly through presentations, written documents, and verbally.
•    Ability to perform root cause analysis and recommendations for non-conforming products.
•    Understanding of product and process change control, MRP / Inventory processes, and Quality System requirements.

Preferred:
•    Lean Champion and/or Six Sigma certifications preferred.
•    Ability to use Mechanical CAD tools (Solidworks or ProE).
•    Ability to read electronics schematics and mechanical drawings.
•    Experience troubleshooting and documenting evaluations of finished devices, sub-assemblies, and component failures.

Will be:

Setting up production lines/ convert production lines

lubricate all machinery

change drive belts, timing belts,

identify potential problems, troubleshoot

maintain sanitation equipment

REQUIREMENTS:

Duties:

> coordinate overall warehouse activities through planning and communication w/ supervisors to ensure all shipping and receiving objectives are accomplished,

> Develops, controls , plans budgets for warehouse

> monitors storage racks, tanks and other structures to ensrue the safe storage of materials

> overses the rotation of inventory to prevent spoilage or outdated products

> controls and minimizes OT labor costs as well as maintianing costs  for out of stock and receiving / selection errors